ClaraBrain™

Health information infrastructure at runtime.

ClaraBrain connects applications and AI systems to structured medical information across specialized sources, when they need it.

Why it matters

Precision starts with the source.

Different sources answer different kinds of questions. ClaraBrain keeps those distinctions intact so systems can work with the appropriate context at runtime.

Resolve

Understand terminology, synonyms, concepts, and ambiguity before retrieval.

Deterministic lexical resolution and terminology normalization help ClaraBrain interpret a request before it moves deeper into the system.

Route

Direct requests toward sources designed for the information being requested.

Different questions belong with different sources. ClaraBrain can route requests across terminology, medications, literature, trials, safety, evidence, and provider information.

Retrieve

Bring relevant health information into a usable runtime context.

Independently maintained medical datasets remain available during system operation without being flattened into one undifferentiated knowledge store.

Trace

Preserve source, version, and provenance context around information.

Source lineage and operational history help retain context about where information originated, which release is installed, and how updates have progressed.

What ClaraBrain can do

Start with a health question.

ClaraBrain can connect a single request with multiple specialized sources when useful, while preserving the role and context of each source.

Medication information

Resolve a medication, retrieve official labeling, examine reported adverse events, connect related clinical terminology, and find supporting medical literature.

RxNorm · DailyMed · FAERS · PubMed · UMLS · SNOMED CT

Laboratory information

Identify a laboratory test, connect it with relevant clinical concepts and conditions, and retrieve supporting literature and curated evidence.

LOINC · SNOMED CT · ICD-11 · UMLS · PubMed · Evidence

Research and clinical trials

Search locally maintained biomedical literature and clinical-trial information across specialized research sources.

PubMed / MEDLINE · ClinicalTrials.gov

Healthcare discovery

Find physicians, specialties, clinics, pharmacies, and geographic healthcare information through a dedicated provider-directory runtime.

ClaraDirectory

Inside ClaraBrain

Specialized health information, maintained from source.

ClaraBrain maintains specialized medical and health-information sources independently so each can preserve its terminology, release model, provenance, and operational state.

Clinical terminology

UMLS · SNOMED CT · ICD-11 · LOINC · HPO

Biomedical concepts, clinical terminology, disease classifications, laboratory observations, and phenotype relationships.

Medications and safety

RxNorm · DailyMed · FAERS

Normalized medications, official drug labeling, prescribing information, and reported adverse-event data.

Research and education

PubMed / MEDLINE · ClinicalTrials.gov · MedlinePlus

Biomedical literature, clinical-study information, and patient-oriented health education.

ClaraBrain services

Lexical · Evidence · ClaraDirectory · Provenance

Terminology resolution, curated evidence, healthcare discovery, and source-lineage context.

Source maintenance

Timely Updates from sources.

Health-information sources do not share one release schedule. ClaraBrain tracks them independently, including installed versions, source checks, successful updates, failures, and retries.

ClinicalTrials.gov

Daily incremental

PubMed / MEDLINE

Incremental

RxNorm

Monthly + weekly capability

LOINC

Weekly release checks

FAERS

Quarterly releases

SNOMED CT

Release-aware

ClaraBrain records which source release is installed and preserves update history rather than treating health information as a single static corpus.

Interactive explainer

Explore how ClaraBrain structures health knowledge.

Select each layer to review how ClaraBrain organizes medical sources, entity relationships, runtime access, evidence pathways, and provenance context.

01

Runtime Knowledge

Health knowledge available during operation

ClaraBrain makes locally maintained medical and health-information resources available while systems are operating, allowing applications to retrieve structured information with source and version context.

What it is

A runtime knowledge environment that makes structured medical information available to applications, tools, and governed interaction surfaces while they are operating.

Where it fits

Used when a system needs current, source-aware health information during operation rather than depending only on information contained in an application or model itself.

ClaraWell provides

  • Health information at runtime
  • Locally maintained medical resources
  • Source and version context
  • Usable information during system operation
02

Medical Sources

Specialized health-information resources

ClaraBrain maintains specialized sources for biomedical terminology, classifications, medications, laboratory observations, phenotypes, adverse events, literature, clinical trials, drug labeling, patient education, evidence, and provider information.

What it is

A collection of independently maintained medical and health-information runtimes, each preserving the terminology, structure, release model, and purpose of its source.

Where it fits

These sources form the information foundation of ClaraBrain. They remain distinct so terminology, medications, literature, trials, safety information, evidence, and provider data can be used according to their individual strengths.

ClaraWell provides

  • Independent medical-source runtimes
  • Source-specific terminology and semantics
  • Local health-data availability
  • Version-aware source maintenance
03

Lexical Resolution

Deterministic terminology resolution

ClaraBrain normalizes language, resolves synonyms and concepts, manages ambiguity, and helps determine how a health-information request should be interpreted before retrieval.

What it is

A deterministic lexical-resolution layer for terminology normalization, synonym handling, concept resolution, ambiguity control, and query routing.

Where it fits

Used between a health-information request and downstream retrieval so different words, phrases, and medical terms can be resolved into a more consistent interpretation.

ClaraWell provides

  • Terminology normalization
  • Synonym and phrase resolution
  • Ambiguity controls
  • Deterministic query routing
04

Search + Retrieval

Find information across specialized sources

ClaraBrain provides search and retrieval infrastructure for locally maintained medical information, allowing systems to locate relevant concepts, literature, trials, medications, evidence, and other health-information resources during operation.

What it is

Search and retrieval infrastructure for querying indexed medical datasets and specialized ClaraBrain resources while preserving the role of the underlying source.

Where it fits

Used after a request has been interpreted and routed, allowing applications and workflows to locate source-appropriate information across ClaraBrain's medical-data environment.

ClaraWell provides

  • Local medical-data search
  • Cross-runtime search capability
  • Indexed retrieval infrastructure
  • Structured information pathways
05

Evidence

Curated evidence and reference relationships

ClaraBrain maintains a dedicated Evidence runtime for governed evidence, controlled clinical explanations, and authoritative reference relationships that remain distinct from raw literature retrieval.

What it is

A dedicated evidence runtime containing internally curated evidence, controlled reference relationships, and authoritative source links.

Where it fits

Used when an application or workflow needs governed evidence context in addition to terminology, source data, or raw medical literature.

ClaraWell provides

  • Curated evidence relationships
  • Controlled reference context
  • Authoritative source links
  • Evidence independent of raw literature search
06

Provenance + Updates

Source and update traceability

ClaraBrain records which source releases are installed and tracks update activity from source detection through ingestion and validation, while preserving failures and retries for review.

What it is

A source-lineage and update-history layer that distinguishes publisher releases, local detection, downloads, ingestion, validation, promotion, failures, and retries.

Where it fits

Used across the medical-data environment so applications and operators can understand what information is installed, when it changed, and how an update progressed.

ClaraWell provides

  • Installed source-version context
  • Publisher and local update history
  • Failure and retry visibility
  • Source lineage and provenance
07

Access

Application and workflow access

ClaraBrain exposes higher-level access to its medical-data and knowledge capabilities so applications, research tools, governed interfaces, and evolving workflows can use specialized information services.

What it is

A higher-level application and service layer for exposing ClaraBrain capabilities to tools, interfaces, and persona-oriented workflows.

Where it fits

Used above ClaraBrain's specialized information services, providing the access point through which applications and future unified workflows can use medical-data and knowledge capabilities.

ClaraWell provides

  • Application access surfaces
  • Support for practitioner and researcher workflows
  • Structured service access
  • Foundation for broader orchestration

Deployment

Give your systems health information at runtime.

ClaraBrain brings specialized medical data into one maintained information environment. Applications and AI systems can access the data they need, when they need it.

The value is practical: less data infrastructure to build and maintain, faster access to source-aware information, and a stronger foundation for safer health and wellness systems.